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COVID19 информация для клиницистов

Клиническое руководство по ведению критически больных взрослых с коронавирусной инфекцией 2019 (COVID-19) / Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Опубликовано: Интернет портал «Новости GMP»

FDA одобрена первая тест-система на коронавирус для самостоятельного тестирования на дому

Опубликовано: AHA/ASA Journals

2022 Interim Guidance to Healthcare Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates with Suspected or Confirmed COVID-19: From the Emergency Cardiovascular Care Committee and Get With the Guidelines®-Resuscitation Adult and Pediatric Task Forces of the American Heart Association in Collaboration with the American Academy of Pediatrics, American Association for Respiratory Care, The Society of Critical Care Anesthesiologists, and American Society of Anesthesiologists

Опубликовано: American Academy of Pediatrics

Delivery Characteristics and the Risk of Early-Onset Neonatal Sepsis

A Quality Improvement Bundle to Improve Outcomes in Extremely Preterm Infants in the First Week

Developing a Quality Improvement Feeding Program for NICU Patients

IVIG Compared With IVIG Plus Infliximab in Multisystem Inflammatory Syndrome in Children

COVID-19 in Children: Initial Characterization of the Pediatric Disease

Epidemiology of COVID-19 Among Children in China

SARS-CoV-2–Induced Kawasaki-Like Hyperinflammatory Syndrome: A Novel COVID Phenotype in Children

Опубликовано: American College of Cardiology (ACC)

COVID-19 Clinical Guidance For the Cardiovascular Care Team

Опубликовано: American Journal of Respiratory and Critical Care Medicine (AJRCCM)

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021

Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline

Hospital Preparedness for COVID-19: A Practical Guide from a Critical Care Perspective

COVID-19 with Different Severity: A Multi-center Study of Clinical Features

Basing Respiratory Management of Coronavirus on Physiological Principles

Clinical Course and Outcomes of 344 Intensive Care Patients with COVID-19

Ventilatory Ratio in Hypercapnic Mechanically Ventilated Patients with COVID-19 Associated ARDS

Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan: A Retrospective Observational Study

The Richmond Agitation - Sedation Scale Validity and Reliability in Adult Intensive Care Unit Patients

SARS-CoV-2: First Do No Harm

Lung Recruitability in COVID-19–associated Acute Respiratory Distress Syndrome: A Single-Center Observational Study

Uncontrolled Innate and Impaired Adaptive Immune Responses in Patients with COVID-19 Acute Respiratory Distress Syndrome

Biological Mechanisms of COVID-19 Acute Respiratory Distress Syndrome

A Call for Rational Intensive Care in the Era of COVID-19

Опубликовано: American Society of Anesthesiologists (ASA)

Fundamentals of Critical Care Nephrology

Initial Ventilator Settings and Adjustments in the ICU

Intubation in COVID

Pulmonary

ICU Ventilation for Anesthesiologists

Ventilator Tracings

INDICATIONS FOR ECMO for ICU COVID-19 PATIENTS

VA ECMO Management “Cheat” Sheet

COVID-19 associated Myocardial Injury

Critical Care for the Non-Critical Care Physician – Endocrine and Steroid Use Topics

INFECTIOUS DISEASES REFRESHER FOR ANESTHESIOLOGISTS

Initial Assessment of Shock Etiology in a Critically Ill Patient

Neurological System Management Overview in the ICU

ASA/SCCM/SOCCA – Heme/Musculoskeletal/Best Practices

Refractory Hypoxemia VV ECMO infographic

Опубликовано: Anesthesiology

Treatments Associated with Lower Mortality among Critically Ill COVID-19 Patients: A Retrospective Cohort Study

Elastomeric Respirators for COVID-19 and the Next Respiratory Virus Pandemic: Essential Design Elements

Perioperative Management of Patients Infected with the Novel Coronavirus: Recommendation from the Joint Task Force of the Chinese Society of Anesthesiology and the Chinese Association of Anesthesiologists

Acute Respiratory Distress Syndrome: Contemporary Management and Novel Approaches during COVID-19

Postoperative Analgesic Effectiveness of Quadratus Lumborum Block for Cesarean Delivery under Spinal Anesthesia: A Systematic Review and Meta-analysis

Опубликовано: Annals of the American Thoracic Society (AnnalsATS)

The Impact of High-Flow Nasal Cannula Use on Patient Mortality and the Availability of Mechanical Ventilators in COVID-19

COVID-19 and Lessons to be Learned from Prior Coronavirus Outbreaks

Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China

COVID-19 Lung Injury and High Altitude Pulmonary Edema: A False Equation with Dangerous Implications

In Defense of Evidence-Based Medicine for the Treatment of COVID-19 ARDS

Опубликовано: AMERICAN THORACIC SOCIETY (ATS)

Evidence That SARS-CoV-2 Induces Lung Cell Senescence: Potential Impact on COVID-19 Lung Disease

Liponucleotides: Promises and Unknowns as Novel Therapeutics for Acute Respiratory Distress Syndrome

Pulmonary Endothelial Dysfunction and Thrombotic Complications in Patients with COVID-19

Lung Epithelial Cell Transcriptional Regulation as a Factor in COVID-19 Associated Coagulopathies

COVID‐19: Interim Guidance on Management Pending Empirical Evidence.

Опубликовано: ATS-SCHOLAR

Just-In-Time Tools for Training Non-Critical Care Providers: Basics of Respiratory Failure

Опубликовано: bioRxiv

Interim Estimates of Vaccine Effectiveness of BNT162b2 and mRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers — Eight U.S. Locations, December 2020–March 2021

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

Опубликовано: BMC

Study find that COVID ARDS was associated with a low risk for possible or proven PCP: still true after dexamethasone use

Effects of prone and lateral positioning alternate in high-flow nasal cannula patients with severe COVID-19

Variation in United States COVID-19 newborn care practices: results of an online physician survey

Noninvasive respiratory support for COVID-19 patients: when, for whom, and how?

Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis

The proteomics of lung injury in childhood: challenges and opportunities

Respiratory effects of lung recruitment maneuvers depend on the recruitment-to-inflation ratio in patients with COVID-19-related acute respiratory distress syndrome

Early, biomarker-guided steroid dosing in COVID-19 Pneumonia: a pilot randomized controlled trial

Prolonged enhancement of cytotoxic T lymphocytes in the post-recovery state of severe COVID-19

Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Effect of COVID-19 on Kawasaki Disease: Decrease Age of Onset and Increase Skin Manifestation

Red flags of poor prognosis in pediatric cases of COVID-19: the first 6610 hospitalized children in Iran/a>

Blood purification could tackle COVID-19?/a>

Benefits and risks of noninvasive oxygenation strategy in COVID-19: a multicenter, prospective cohort study (COVID-ICU) in 137 hospitals

Опубликовано: Cell Press

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Journal Pre-proof Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19

Опубликовано: Centers for Desease Control and Prevention

Pregnant and Recently Pregnant People

CDC Real-World Study Confirms Protective Benefits of mRNA COVID-19 Vaccines

Interim Estimates of Vaccine Effectiveness of BNT162b2 and mRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers — Eight U.S. Locations, December 2020–March 2021

Myths and Facts about COVID-19 Vaccines

Опубликовано: Cochrane Library

Coronavirus (COVID-19): evidence relevant to critical care

Опубликовано: Clinical Immunology

Studying the coagulopathy of COVID-19

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial

Evaluation of early antibiotic use in non-severe COVID-19 patients without bacterial infection: Early antibiotic use in non-severe COVID-19

Change in Antimicrobial Use During COVID-19 Pandemic in South Carolina Hospitals: A Multicenter Observational Cohort Study

Evaluation of early antibiotic use in non-severe COVID-19 patients without bacterial infection: Early antibiotic use in non-severe COVID-19

Hydroxychloroquine plus azithromycin early treatment of mild COVID-19 in outpatient setting: a randomized, double-blinded, placebo-controlled clinical trial evaluating viral clearance

Potential effect of blood purification therapy in reducing cytokine storm as a late complication of critically ill COVID-19

Опубликовано: eLife

SARS-CoV-2 strategically mimics proteolytic activation of human ENaC

Опубликовано: European Heart Journal

Coronaviruses and the cardiovascular system: acute and long-termimplications

Опубликовано: Food and Drug Administration

Coronavirus (COVID-19) Update: FDA Takes Additional Actions on the Use of a Booster Dose for COVID-19 Vaccines

Investigational COVID-19 Convalescent Plasma

Coronavirus (COVID-19) Update: FDA Authorizes First COVID-19 Test for Self-Testing at Home

Опубликовано: International Journal of Antimicrobial Agents

Scent of a vaccine

Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Successful treatment of plasma exchange followed by intravenous immunogloblin in a critically ill patient with 2019 novel coronavirus infection

Drug repositioning is an alternative for the treatment of coronavirus COVID-19

The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality

Recent progress in understanding 2019 novel coronavirus (SARS-CoV-2) associated with human respiratory disease: detection, mechanisms and treatment

Complex emergencies of COVID-19: management and experience in Zhuhai, China

The epidemiology, diagnosis and treatment of COVID-19

Global coronavirus disease 2019: what has daily cumulative index taught us?

Cytokine storm and immunomodulatory therapy in COVID-19: Role of chloroquine and anti-IL-6 monoclonal antibodies

Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19

Arbidol: A potential antiviral drug for the treatment of SARS-CoV-2 by blocking the trimerization of viral spike glycoprotein ?

May drug-related cardiovascular toxicities persist after hospital discharge in COVID-19 patients?

SARS-CoV-2 was already spreading in France in late December 2019

Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal

Computational screening of antagonists against the SARS-CoV-2 (COVID-19) coronavirus by molecular docking

Neutrophil-to-lymphocyte ratio and clinical outcome in COVID-19: a report from the Italian front line

IS TEICOPLANIN A COMPLEMENTARY TREATMENT OPTION FOR COVID-19? THE QUESTION REMAINS

Extra-respiratory manifestations of COVID-19

A review on possible modes of actions of Chloroquine/ Hydroxychloroquine: Repurposing against SAR-COV-2 (COVID 19) pandemic

Side effects of ruxolitinib in patients with SARS-CoV-2 infection: two case reports

Tocilizumab administration in a refractory case of COVID-19

Procalcitonin levels in COVID-19 patients

Macrolides and viral infections: focus on azithromycin in COVID-19 pathology

Potential of coronavirus 3C-like protease inhibitors for the development of new anti-SARS-CoV-2 drugs: Insights from structures of protease and inhibitors

Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2): A global pandemic and treatments strategies

COVID-19 Treatment: Close to a Cure? – A Rapid Review of Pharmacotherapies for the Novel Coronavirus

Corticosteroid therapy for patients with CoVID-19 pneumonia: a before-after study

A pharmacological perspective of Chloroquine in SARS-CoV-2 infection

Chloroquine and Hydroxychloroquine in Coronavirus Disease 2019 (COVID-19). Facts, Fiction & the Hype. A Critical Appraisal.

Reply to Gautret et al: hydroxychloroquine sulfate and azithromycin for COVID-19: what is the evidence and what are the risks?

Diagnostic performance of initial blood urea nitrogen combined with D-Dimer levels for predicting in-hospital mortality in COVID-19 patients

Ribavirin Therapy For Severe COVID-19: A Retrospective Cohort Study

Tocilizumab for severe COVID-19: a systematic review and meta-analysis

Widely available lysosome targeting agents should be considered as potential therapy for COVID-19

No evidence of SARS-CoV-2 circulation before the identification of the first Swiss SARS-CoV-2 case.

Impact of medical care including anti-infective agents use on the prognosis of COVID-19 hospitalized patients over time

In silico Study of Azithromycin, Chloroquine and Hydroxychloroquine and their Potential Mechanisms of Action against SARS-CoV-2 Infection

Recommendations for use of a hydroxychloroquine loading dose in patients with COVID-19

Repurposing of host-based therapeutic agents for the treatment of coronavirus disease 2019 (COVID-19): A link between antiviral and anticancer mechanisms?

Lactoferrin as potential preventative and treatment for COVID-19

Predictive factors for cardiac conduction abnormalities with hydroxychloroquine-containing combinations for COVID-19

NSafety and Effectiveness of Azithromycin in Patients with COVID-19: an open-label randomized trial

Antimicrobial stewardship program, a vital resource for hospitals during the global outbreak of Coronavirus Disease 2019 (COVID-19)

Projected supportive effects of Pycnogenol® in patients suffering from multi-dimensional health impairments after a SARS-CoV2 infection

Azithromycin and Ambroxol as potential pharmacotherapy for ARS-CoV-2

Therapeutic Modalities and Novel Approaches in Regenerative Medicine for COVID-19

Frequency of Long QT in Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine: a Meta-analysis

LPD-12, a Promising Lipopeptide to Control COVID-19

Post Exposure Prophylaxis with Hydroxychloroquine (HCQ) for the Prevention of COVID-19, a Myth or a Reality? The PEP-CQ Study

COVID-19 outpatients: early risk-stratified treatment with zinc plus low-dose hydroxychloroquine and azithromycin: a retrospective case series study

Pattern of SARS-CoV-2 infection among dependant elderly residents living in long-term care facilities in Marseille, France, March–June 2020

Plasma exchange in the treatment of complex COVID-19 related critical illness: controversies and perspectives

Different mutations in SARS-CoV-2 associate with severe and mild outcome

Vertical transmission and kidney damage in newborns from coronavirus disease 2019 infection pregnant mother

Опубликовано: JAMA Networks

Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection

Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants

Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications

Clinical Characteristics and Outcomes of Patients With COVID-19–Associated Acute Respiratory Distress Syndrome Who Underwent Lung Transplant

Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021

Multisystem Inflammatory Syndrome in Children by COVID-19 Vaccination Status of Adolescents in France

Immunogenicity of Extended mRNA SARS-CoV-2 Vaccine Dosing Intervals

Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non–Critically Ill Hospitalized Patients With COVID-19A Randomized Clinical Trial

A National Strategy for COVID-19Testing, Surveillance, and Mitigation Strategies

A National Strategy for the “New Normal” of Life With COVID

A National Strategy for COVID-19 Medical CountermeasuresVaccines and Therapeutics

The First 2 Years of COVID-19Lessons to Improve Preparedness for the Next Pandemic

Durability of Antibody Levels After Vaccination With mRNA SARS-CoV-2 Vaccine in Individuals With or Without Prior Infection

Questions Remain About Who Will Get Monoclonal Antibodies for COVID-19 Preexposure Prophylaxis

Metabolic Syndrome and Acute Respiratory Distress Syndrome in Hospitalized Patients With COVID-19

Surveillance for Adverse Events After COVID-19 mRNA Vaccination

Antibody Response and Variant Cross-Neutralization After SARS-CoV-2 Breakthrough Infection

Treating the Most Critically Ill Patients With COVID-19. The Evolving Role of Extracorporeal Membrane Oxygenation

COVID-19 and Pregnancy

Efficacy of Inhaled Ciclesonide for Outpatient Treatment of Adolescents and Adults With Symptomatic COVID-19A Randomized Clinical Trial

COVID-19 Vaccine Highly Effective Against Adolescent Hospitalizations

Seroprevalence of SARS-CoV-2 Antibodies Among Children in School and Day Care in Montreal, Canada

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 InfectionThe INTERCOVID Multinational Cohort Study

Antibody Titers Before and After a Third Dose of the SARS-CoV-2 BNT162b2 Vaccine in Adults Aged ≥60 Years

Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19The ACTIV-4B Randomized Clinical Trial

Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19A Randomized Clinical Trial

Antithrombotic Therapy for Outpatients With COVID-19Implications for Clinical Practice and Future Research

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe HypoxemiaThe COVID STEROID 2 Randomized Trial

Comparison of SARS-CoV-2 Antibody Response Following Vaccination With BNT162b2 and mRNA-1273

Incidence Rates, Household Infection Risk, and Clinical Characteristics of SARS-CoV-2 Infection Among Children and Adults in Utah and New York City, New York

Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19A Meta-analysis

Association of the COVID-19 Pandemic With Routine Childhood Vaccination Rates and Proportion Up to Date With Vaccinations Across 8 US Health Systems in the Vaccine Safety Datalink

India’s New COVID-19 DNA Vaccine for Adolescents and Adults Is a First

COVID-19 Vaccination of Minors Without Parental ConsentRespecting Emerging Autonomy and Advancing Public Health

Delta Variant Linked With Spike in Youth Hospitalizations

Changes in Adverse Pregnancy Outcomes Associated With the COVID-19 Pandemic in the United States

Interpreting SARS-CoV-2 Test Results

Changes in Body Mass Index Among Children and Adolescents During the COVID-19 Pandemic

Association Between BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women

COVID-19 Transmission Dynamics Among Close Contacts of Index Patients With COVID-19A Population-Based Cohort Study in Zhejiang Province, China

Influenza’s Unprecedented Low Profile During COVID-19 Pandemic Leaves Experts Wondering What This Flu Season Has in Store

Myocarditis and Pericarditis After Vaccination for COVID-19

Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection

Confronting the Delta Variant of SARS-CoV-2, Summer 2021

Study Suggests Lasting Immunity After COVID-19, With a Big Boost From Vaccination

Variation of National and International Guidelines on Respiratory Protection for Health Care Professionals During the COVID-19 Pandemic

Potential Benefits of Expanded COVID-19 Surveillance in the US

Myocarditis and Pericarditis After Vaccination for COVID-19

Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection

The Need for Life-Course Study of Children Born to Mothers With Prior COVID-19 Infection

Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19

Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities

Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults

US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021

Association Between Vaccination With BNT162b2 and Incidence of Symptomatic and Asymptomatic SARS-CoV-2 Infections Among Health Care Workers

Lung Transplants for COVID-19—The Option of Last Resort

Sperm Parameters Before and After COVID-19 mRNA Vaccination

Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19A Randomized Clinical Trial

Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women

Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients

Bamlanivimab for Prevention of COVID-19

Bamlanivimab for Prevention of COVID-19

Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities

Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in AdultsA Randomized Clinical Trial

Allergic Reactions to mRNA Vaccines

Public Trust and Willingness to Vaccinate Against COVID-19 in the US From October 14, 2020, to March 29, 2021

Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 InfectionResults From the Big Ten COVID-19 Cardiac Registry

Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure

COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough

SARS-CoV-2–Specific Antibodies in Breast Milk After COVID-19 Vaccination of Breastfeeding Women

Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission

Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19

COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough

Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers

Assessment of Acute Kidney Injury and Longitudinal Kidney Function After Hospital Discharge Among Patients With and Without COVID-19

Saliva Tests Comparable With Nasal Swabs for SARS-CoV-2 Detection

Prolonged SARS-CoV-2 Infection in a CAR T-Cell Therapy Recipient

COVID-19 “Liquid Biopsy” Could Offer Monitoring, Prognostic Tool

Monoclonal Antibodies for COVID-19

Association of Acute Symptoms of COVID-19 and Symptoms of Depression in Adults

Risk Factors Associated With SARS-CoV-2 Seropositivity Among US Health Care Personnel

Association of Age With Likelihood of Developing Symptoms and Critical Disease Among Close Contacts Exposed to Patients With Confirmed SARS-CoV-2 Infection in Italy

Acute Allergic Reactions to mRNA COVID-19 Vaccines

CDC Interim Recommendations for Fully Vaccinated PeopleAn Important First Step

Characteristics of and Mortality Associated With Diabetic Ketoacidosis Among US Patients Hospitalized With or Without COVID-19

Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

Management of COVID-19 Respiratory Distress

Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

The Risks of Prescribing Hydroxychloroquine for Treatment of COVID-19—First, Do No Harm

Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset

COVID-19 and Risks Posed to Personnel During Endotracheal Intubation

Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection

Variation in COVID-19 Hospitalizations and Deaths Across New York City Boroughs

Exposure to a Surrogate Measure of Contamination From Simulated Patients by Emergency Department Personnel Wearing Personal Protective Equipment

Randomized Clinical Trials and COVID-19

The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”)

Privileges and Immunity Certification During the COVID-19 Pandemic

Choices for the “New Normal”

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents

Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State

N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel

Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn

Antibodies in Infants Born to Mothers With COVID-19 Pneumonia

COVID-19 and Postinfection Immunity

Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit

Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease 2019

Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection

Emergency Use Authorization of Remdesivir

Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit

Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure

An Ethical Framework for Allocating Scarce Inpatient Medications for COVID-19 in the US

Is the Prone Position Helpful During Spontaneous Breathing in Patients With COVID-19?

Interpreting Diagnostic Tests for SARS-CoV-2

Changes in SARS-CoV-2 Positivity Rate in Outpatients in Seattle and Washington State, March 1-April 16, 2020

From Mitigation to Containment of the COVID-19 Pandemic

Detection of SARS-CoV-2 in Different Types of Clinical Specimens

Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)

Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China

Predictive Mathematical Models of the COVID-19 Pandemic

Planning for a COVID-19 Vaccination Program

Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics

Postmortem Examination of Patients With COVID-19

Olfactory Dysfunction in COVID-19

Seroprevalence of SARS-CoV-2–Specific Antibodies Among Adults in Los Angeles County, California, on April 10-11, 2020

Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults

Labor and Delivery Visitor Policies During the COVID-19 Pandemic

Translating Science on COVID-19 to Improve Clinical Care and Support the Public Health Response

Prioritizing Physician Mental Health as COVID-19 Marches On

Digital Smartphone Tracking for COVID-19

Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection

Comparison of Clinical Characteristics of Patients with Asymptomatic vs Symptomatic Coronavirus Disease 2019 in Wuhan, China

Coronavirus Disease 2019 Test Results After Clinical Recovery and Hospital Discharge Among Patients in China

Modeling Epidemics With Compartmental Models

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure

Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19

Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain

Anthony Fauci, MD, on COVID-19 Vaccines, Schools, and Larry Kramer

Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City

Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019

Renin-Angiotensin-Aldosterone Inhibitors and Susceptibility to and Severity of COVID-19

Temperature, Humidity, and Latitude Analysis to Estimate Potential Spread and Seasonality of Coronavirus Disease 2019 (COVID-19)

Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality

Thromboelastographic Results and Hypercoagulability Syndrome in Patients With Coronavirus Disease 2019 Who Are Critically Ill

Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020

Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza

Neurologic and Radiographic Findings Associated With COVID-19 Infection in Children

Is a “Cytokine Storm” Relevant to COVID-19?

Mortality and Morbidity

Cognitive Bias and Public Health Policy During the COVID-19 Pandemic

Excess Deaths From COVID-19 and Other Causes, March-April 2020

Benefits and Safety of Nasal Saline Irrigations in a Pandemic—Washing COVID-19 Away

Fear of Coronavirus Disease 2019—An Emerging Cardiac Risk

Presence of Genetic Variants Among Young Men With Severe COVID-19

Ketoacidosis in Children and Adolescents With Newly Diagnosed Type 1 Diabetes During the COVID-19 Pandemic in Germany

Molecular Underpinnings of Severe Coronavirus Disease 2019

Pooling Data From Individual Clinical Trials in the COVID-19 Era

Serosurveillance and the COVID-19 Epidemic in the US

Trends in US Heart Transplant Waitlist Activity and Volume During the Coronavirus Disease 2019 (COVID-19) Pandemic

Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System

Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers

COVID-19 and Dexamethasone A Potential Strategy to Avoid Steroid-Related Strongyloides Hyperinfection

Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19)

Prevalence of SARS-CoV-2 Antibodies in Health Care Personnel in the New York City Area

Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency

SARS-CoV-2 Testing and Changes in Primary Care Services in a Multistate Network of Community Health Centers During the COVID-19 Pandemic

Emergency Use Authorizations During the COVID-19 Pandemic Lessons From Hydroxychloroquine for Vaccine Authorization and Approval

Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

Clinical Outcomes in Young US Adults Hospitalized With COVID-19

Flipping the Script for Coronavirus Disease 2019 Contact Tracing

National Academies Offers Strategies to Encourage Cooperation in COVID-19 Contact Tracing

COVID-19 and the Path to Immunity

Cardiovascular Magnetic Resonance Findings in Competitive Athletes Recovering From COVID-19 Infection

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19

In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2

SARS-CoV-2 Nasopharyngeal Swab Testing—False-Negative Results From a Pervasive Anatomical Misconception

Frequency of Children vs Adults Carrying Severe Acute Respiratory Syndrome Coronavirus 2 Asymptomatically

Should We Mandate a COVID-19 Vaccine for Children?

Oncology Clinical Transformation in Response to the COVID-19 Pandemic

Change in Antibodies to SARS-CoV-2 Over 60 Days Among Health Care Personnel in Nashville, Tennessee

Nephrology and COVID-19

Cardiology and COVID-19

Internal Medicine and COVID-19

Pediatrics and COVID-19

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19

Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19

Association Between Number of In-Person Health Care Visits and SARS-CoV-2 Infection in Obstetrical Patients

Asymptomatic and Presymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infection Rates in a Multistate Sample of Skilled Nursing Facilities

Time to Reassess Tocilizumab’s Role in COVID-19 Pneumonia

Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia

Scientific and Ethical Principles Underlying Recommendations From the Advisory Committee on Immunization Practices for COVID-19 Vaccination Implementation

Corticosteroids in COVID-19 ARDS

The Challenges of Expanding Rapid Tests to Curb COVID-19

COVID-19 Halts Reproductive Care for Millions of Women

Herd Immunity and Implications for SARS-CoV-2 Control

First It Was Masks; Now Some Refuse Testing for SARS-CoV-2

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19

Hospital-Acquired SARS-CoV-2 Infection

COVID-19 as the Leading Cause of Death in the United States

National Trends in the US Public’s Likelihood of Getting a COVID-19 Vaccine—April 1 to December 8, 2020

Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine

Can We Protect Pregnant Women and Young Infants From COVID-19 Through Maternal Immunization?

Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19

The Johnson & Johnson Vaccine for COVID-19

Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2

Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children

The Potential Future of the COVID-19 Pandemic

Filtering Facepiece Respirator (N95 Respirator) Reprocessing

Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

Outcomes for Patients Following Hospitalization for COVID-19

Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit

Respiratory Support During the COVID-19 Pandemic

Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure

Опубликовано: Johns Hopkins Bloomberg School of Public Health

Five Variables that Can Affect COVID-19 Symptoms, Prognosis, and Outcomes

Опубликовано: Critical Care Medicine

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update

Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update

Опубликовано: Lilly Investors

Lilly's neutralizing antibody bamlanivimab (LY-CoV555) receives FDA emergency use authorization for the treatment of recently diagnosed COVID-19

Опубликовано: Mayo Clinic Proceedings

Urgent Guidance for Navigating and Circumventing the QTc Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for COVID-19

Опубликовано: Medical Xpress

COVID-19 vaccine given during pregnancy guards against severe COVID in newborns

Real-world data confirms Pfizer vaccine is safe for kids ages 5-11

Study shows people infected with Omicron may be less susceptible to Delta variant

Scientists identify antibodies that can neutralize omicron

Researchers pinpoint blood factors linked to severe COVID

What makes an mRNA vaccine so effective against severe COVID-19?

Requirement for adults to wear masks in schools has major impact on COVID-19 transmissions, study finds

Respiratory tract bacterial extracts could prevent COVID-19

New COVID test more than 99 percent accurate

Molecule from approved malaria medicine protects lung cells against COVID-19

New study may help explain why infants are less affected by COVID than adults

Two common compounds show effectiveness against COVID-19 virus in early testing

COVID-19 case severity: How genetic differences leave immune cells at a disadvantage

Prompt procurement and roll-out of COVID-19 vaccines are as important as their efficacy

Interferon does not improve outcomes for hospitalized adults with COVID-19

Vaccinated groups at highest risk of Covid-19 hospitalisation and death identified using new QCovid tool

COVID-19, not vaccination, presents biggest blood clot risks: study

Vaccinated groups at highest risk of Covid-19 hospitalisation and death identified using new QCovid tool

Study suggests Delta does not cause more severe childhood COVID

Largest real-world study of COVID-19 vaccine safety published

Rotating presence at school, work limits COVID spread: study

Long COVID symptoms likely caused by Epstein-Barr virus reactivation

Many COVID-19 patients produce immune responses against their body's tissues or organs

Genome sequencing shows coronavirus variation drives pandemic surges

COVID-19 death counts 'substantial underestimation' of actual deaths for some Italian regions

Placentas from COVID-19-positive pregnant women show injury

Study suggests wastewater at treatment plants can be used as a barometer for COVID-19 infection rates

Faster identification and isolation of COVID-19 symptomatic individuals found to shorten average serial interval

Scientists discover key element of strong antibody response to COVID-19

We thought COVID-19 was just a respiratory virus—we were wrong

Опубликовано: medRxiv

Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection

Presence of SARS-CoV-2 reactive T cells in COVID-19 patients and healthy donors

Опубликовано: Nature

A dynamic COVID-19 immune signature includes associations with poor prognosis

A guide to immunotherapy for COVID-19

Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2

Omicron overpowers key COVID antibody treatments in early tests

Heavily mutated Omicron variant puts scientists on alert

COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types

COVID super-immunity: one of the pandemic’s great puzzles

COVID vaccine immunity is waning — how much does that matter?

Rogue antibodies involved in almost one-fifth of COVID deaths

Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome

Antibodies reveal who’s protected by Moderna’s COVID vaccine

Long COVID in a prospective cohort of home-isolated patients

Pfizer COVID vaccine protects against worrying coronavirus variants

How could a COVID vaccine cause blood clots? Scientists race to investigate

What it will take to vaccinate the world against COVID-19

COVID-19 and the cardiovascular system

Pick of the coronavirus papers: Immune system shows abnormal response to COVID-19

The race for coronavirus vaccines: a graphical guide

Convalescent serum lines up as first-choice treatment for coronavirus

A human monoclonal antibody blocking SARS-CoV-2 infection

Profile of a killer: the complex biology powering the coronavirus pandemic

An interpretable mortality prediction model for COVID-19 patients

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

COVID-vaccine results are on the way — and scientists’ concerns are growing

Unsustainable charcoal, COVID spreads on plane and antibody cocktails

COVID19: an announced pandemic

SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition

The race to make COVID antibody therapies cheaper and more potent

What Pfizer’s landmark COVID vaccine results mean for the pandemic

Why do COVID death rates seem to be falling?

COVID vaccine excitement builds as Moderna reports third positive result

Genetic mechanisms of critical illness in Covid-19

COVID antibody treatments show promise for preventing severe disease

Опубликовано: NBCNEWS

What's New in the Guidelines

NIH researchers identify potential new antiviral drug for COVID-19

Опубликовано: National Institutes of Health (NIH)

Hyperimmune intravenous immunoglobulin does not improve outcomes for adults hospitalized with COVID-19

Clinical trial of therapeutics for severely ill hospitalized COVID-19 patients begins

Clinical trial of therapeutics for severely ill hospitalized COVID-19 patients begins

NIH trial of anti-CD14 antibody to treat COVID-19 respiratory disease begins

NIH clinical trial shows Remdesivir accelerates recovery from advanced COVID-19

NIH begins clinical trial of hydroxychloroquine and azithromycin to treat COVID-19

Peer-reviewed data shows remdesivir for COVID-19 improves time to recovery

Experimental COVID-19 vaccine safe, generates immune response

Experimental COVID-19 vaccine protects upper and lower airways in nonhuman primates

NIH clinical trial testing remdesivir plus interferon beta-1a for COVID-19 treatment begins

Phase 3 Clinical Testing in the US of AstraZeneca COVID-19 Vaccine Candidate Begins

Fourth large-scale COVID-19 vaccine trial begins in the United States

NIH expands clinical trials to test convalescent plasma against COVID-19

Investigational COVID-19 vaccine well-tolerated and generates immune response in older adults

NIH RADx initiative advances six new COVID-19 testing technologies

Hydroxychloroquine does not benefit adults hospitalized with COVID-19

NIH expands research to improve COVID-19 testing among underserved and vulnerable populations

Results of NIH-sponsored ACTIV-3 trial published

Peer-reviewed report on Moderna COVID-19 vaccine publishes

Four potential COVID-19 therapeutics enter Phase 2/3 testing in NIH ACTIV-2 trial

Most COVID-19 hospitalizations due to four conditions

How Immunity Generated from COVID-19 Vaccines Differs from an Infection

Опубликовано: NIH Director's Blog

EHow Immunity Generated from COVID-19 Vaccines Differs from an Infection

Enlisting Monoclonal Antibodies in the Fight Against COVID-19

Will Warm Weather Slow Spread of Novel Coronavirus?

First Molecular Profiles of Severe COVID-19 Infections

Researchers Publish Encouraging Early Data on COVID-19 Vaccine

Immune T Cells May Offer Lasting Protection Against COVID-19

Study Ties COVID-19-Related Syndrome in Kids to Altered Immune System

Israeli Study Offers First Real-World Glimpse of COVID-19 Vaccines in Action

Infections with ‘U.K Variant’ B.1.1.7 Have Greater Risk of Mortality

Опубликовано: New England Journal of Medicine

https://www.nejm.org/doi/full/10.1056/NEJMoa2103784">Early Convalescent Plasma for High-Risk Outpatients with Covid-19

 

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19

Опубликовано: PubMed

Protecting Healthcare Workers From SARS-CoV-2 Infection: Practical Indications

Опубликовано: Regeneron

Regeneron's REGN-COV2 Antibody Cocktail Reduced Viral Levels and Improved Symptoms in Non-Hospitalized COVID-19 Patients

Опубликовано: Science

Senolytics reduce coronavirus-related mortality in old mice

A Phase 2a clinical trial of Molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

‘Patience is crucial’: Why we won’t know for weeks how dangerous Omicron is

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

Reducing transmission of SARS-CoV-2

Combination prevention for COVID-19

Serology assays to manage COVID-19

Rapid repurposing of drugs for COVID-19

Ethics and governance for digital disease surveillance

Susceptible supply limits the role of climate in the early SARS-CoV-2 pandemic

Which interventions work best in a pandemic?

Introductions and early spread of SARS-CoV-2 in the New York City area

A strategic approach to COVID-19 vaccine R&D

Inhibition of Bruton tyrosine kinase in patients with severe COVID-19

The story of COVID-19: A comparative analysis

An ACE therapy for COVID-19

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

A mathematical model reveals the influence of population heterogeneity on herd immunity to SARS-CoV-2

Broad neutralization of SARS-related viruses by human monoclonal antibodies

Опубликовано: Society of Critical Care Medicine

Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis

Innovating Consistency in Care Through the STOP-VIRUS ICU Learning Collaborative

Опубликовано: Springer

Assessment of heart rate, acidosis, consciousness, oxygenation, and respiratory rate to predict noninvasive ventilation failure in hypoxemic patients

Опубликовано: The Lancet

Considerations in boosting COVID-19 vaccine immune responses

COVID-19: consider cytokine storm syndromes and immunosuppression

Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study

Опубликовано: The Liverpool Drug Interaction Group

Interactions with Experimental COVID-19 Therapies (PART1)

Interactions with Experimental COVID-19 Therapies (PART2)

Опубликовано: Wiley Online Library

Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy


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