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COVID19 информация для клиницистов

Клиническое руководство по ведению критически больных взрослых с коронавирусной инфекцией 2019 (COVID-19) / Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Опубликовано: American Academy of Pediatrics

COVID-19 in Children: Initial Characterization of the Pediatric Disease

Epidemiology of COVID-19 Among Children in China

SARS-CoV-2–Induced Kawasaki-Like Hyperinflammatory Syndrome: A Novel COVID Phenotype in Children

Опубликовано: American College of Cardiology (ACC)

COVID-19 Clinical Guidance For the Cardiovascular Care Team

Опубликовано: American Journal of Respiratory and Critical Care Medicine (AJRCCM)

Hospital Preparedness for COVID-19: A Practical Guide from a Critical Care Perspective

COVID-19 with Different Severity: A Multi-center Study of Clinical Features

Basing Respiratory Management of Coronavirus on Physiological Principles

Clinical Course and Outcomes of 344 Intensive Care Patients with COVID-19

Ventilatory Ratio in Hypercapnic Mechanically Ventilated Patients with COVID-19 Associated ARDS

Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan: A Retrospective Observational Study

The Richmond Agitation - Sedation Scale Validity and Reliability in Adult Intensive Care Unit Patients

An Asymptomatic Patient Infected with Coronavirus Disease 2019

SARS-CoV-2: First Do No Harm

Lung Recruitability in COVID-19–associated Acute Respiratory Distress Syndrome: A Single-Center Observational Study

Опубликовано: American Journal of Respiratory Cell and Molecular Biology (AJRCMB)

A Call for Rational Intensive Care in the Era of COVID-19

Опубликовано: American Society of Anesthesiologists (ASA)

Fundamentals of Critical Care Nephrology

Initial Ventilator Settings and Adjustments in the ICU

Intubation in COVID


ICU Ventilation for Anesthesiologists

Ventilator Tracings


VA ECMO Management “Cheat” Sheet

COVID-19 associated Myocardial Injury

Critical Care for the Non-Critical Care Physician – Endocrine and Steroid Use Topics


Initial Assessment of Shock Etiology in a Critically Ill Patient

Neurological System Management Overview in the ICU

ASA/SCCM/SOCCA – Heme/Musculoskeletal/Best Practices

Refractory Hypoxemia VV ECMO infographic

Опубликовано: Anesthesiology

Perioperative Management of Patients Infected with the Novel Coronavirus: Recommendation from the Joint Task Force of the Chinese Society of Anesthesiology and the Chinese Association of Anesthesiologists

Опубликовано: Annals of the American Thoracic Society (AnnalsATS)

COVID-19 and Lessons to be Learned from Prior Coronavirus Outbreaks

Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China

COVID-19 Lung Injury and High Altitude Pulmonary Edema: A False Equation with Dangerous Implications

In Defense of Evidence-Based Medicine for the Treatment of COVID-19 ARDS


COVID‐19: Interim Guidance on Management Pending Empirical Evidence.

Опубликовано: ATS-SCHOLAR

Just-In-Time Tools for Training Non-Critical Care Providers: Basics of Respiratory Failure

Опубликовано: bioRxiv

A human monoclonal antibody blocking SARS-CoV-2 infectiоn

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

Опубликовано: Clinical Immunology

Potential effect of blood purification therapy in reducing cytokine storm as a late complication of critically ill COVID-19

Опубликовано: eLife

SARS-CoV-2 strategically mimics proteolytic activation of human ENaC

Опубликовано: European Heart Journal

Coronaviruses and the cardiovascular system: acute and long-termimplications

Опубликовано: Food and Drug Administration

Investigational COVID-19 Convalescent Plasma

Опубликовано: International Journal of Antimicrobial Agents

Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Successful treatment of plasma exchange followed by intravenous immunogloblin in a critically ill patient with 2019 novel coronavirus infection

Drug repositioning is an alternative for the treatment of coronavirus COVID-19

The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality

Recent progress in understanding 2019 novel coronavirus (SARS-CoV-2) associated with human respiratory disease: detection, mechanisms and treatment

Complex emergencies of COVID-19: management and experience in Zhuhai, China

The epidemiology, diagnosis and treatment of COVID-19

Global coronavirus disease 2019: what has daily cumulative index taught us?

Cytokine storm and immunomodulatory therapy in COVID-19: Role of chloroquine and anti-IL-6 monoclonal antibodies

Pharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19

Arbidol: A potential antiviral drug for the treatment of SARS-CoV-2 by blocking the trimerization of viral spike glycoprotein ?

May drug-related cardiovascular toxicities persist after hospital discharge in COVID-19 patients?

SARS-CoV-2 was already spreading in France in late December 2019

Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal

Computational screening of antagonists against the SARS-CoV-2 (COVID-19) coronavirus by molecular docking

Neutrophil-to-lymphocyte ratio and clinical outcome in COVID-19: a report from the Italian front line


Extra-respiratory manifestations of COVID-19

A review on possible modes of actions of Chloroquine/ Hydroxychloroquine: Repurposing against SAR-COV-2 (COVID 19) pandemic

Side effects of ruxolitinib in patients with SARS-CoV-2 infection: two case reports

Tocilizumab administration in a refractory case of COVID-19

Procalcitonin levels in COVID-19 patients

Macrolides and viral infections: focus on azithromycin in COVID-19 pathology

Potential of coronavirus 3C-like protease inhibitors for the development of new anti-SARS-CoV-2 drugs: Insights from structures of protease and inhibitors

Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2): A global pandemic and treatments strategies

COVID-19 Treatment: Close to a Cure? – A Rapid Review of Pharmacotherapies for the Novel Coronavirus

Corticosteroid therapy for patients with CoVID-19 pneumonia: a before-after study

A pharmacological perspective of Chloroquine in SARS-CoV-2 infection

Chloroquine and Hydroxychloroquine in Coronavirus Disease 2019 (COVID-19). Facts, Fiction & the Hype. A Critical Appraisal.

Reply to Gautret et al: hydroxychloroquine sulfate and azithromycin for COVID-19: what is the evidence and what are the risks?

Diagnostic performance of initial blood urea nitrogen combined with D-Dimer levels for predicting in-hospital mortality in COVID-19 patients

Ribavirin Therapy For Severe COVID-19: A Retrospective Cohort Study

Tocilizumab for severe COVID-19: a systematic review and meta-analysis

Widely available lysosome targeting agents should be considered as potential therapy for COVID-19

No evidence of SARS-CoV-2 circulation before the identification of the first Swiss SARS-CoV-2 case.

Impact of medical care including anti-infective agents use on the prognosis of COVID-19 hospitalized patients over time

In silico Study of Azithromycin, Chloroquine and Hydroxychloroquine and their Potential Mechanisms of Action against SARS-CoV-2 Infection

Recommendations for use of a hydroxychloroquine loading dose in patients with COVID-19

Repurposing of host-based therapeutic agents for the treatment of coronavirus disease 2019 (COVID-19): A link between antiviral and anticancer mechanisms?

Lactoferrin as potential preventative and treatment for COVID-19

Predictive factors for cardiac conduction abnormalities with hydroxychloroquine-containing combinations for COVID-19

NSafety and Effectiveness of Azithromycin in Patients with COVID-19: an open-label randomized trial

Antimicrobial stewardship program, a vital resource for hospitals during the global outbreak of Coronavirus Disease 2019 (COVID-19)

Опубликовано: JAMA Networks

Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

Management of COVID-19 Respiratory Distress

Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

The Risks of Prescribing Hydroxychloroquine for Treatment of COVID-19—First, Do No Harm

Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset

COVID-19 and Risks Posed to Personnel During Endotracheal Intubation

Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection

Variation in COVID-19 Hospitalizations and Deaths Across New York City Boroughs

Exposure to a Surrogate Measure of Contamination From Simulated Patients by Emergency Department Personnel Wearing Personal Protective Equipment

Randomized Clinical Trials and COVID-19

The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”)

Privileges and Immunity Certification During the COVID-19 Pandemic

Choices for the “New Normal”

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents

Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State

N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel

Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn

Antibodies in Infants Born to Mothers With COVID-19 Pneumonia

COVID-19 and Postinfection Immunity

Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit

Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease 2019

Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection

Emergency Use Authorization of Remdesivir

Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit

Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure

An Ethical Framework for Allocating Scarce Inpatient Medications for COVID-19 in the US

Is the Prone Position Helpful During Spontaneous Breathing in Patients With COVID-19?

Interpreting Diagnostic Tests for SARS-CoV-2

Changes in SARS-CoV-2 Positivity Rate in Outpatients in Seattle and Washington State, March 1-April 16, 2020

From Mitigation to Containment of the COVID-19 Pandemic

Detection of SARS-CoV-2 in Different Types of Clinical Specimens

Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)

Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China

Predictive Mathematical Models of the COVID-19 Pandemic

Planning for a COVID-19 Vaccination Program

Treating COVID-19—Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics

Postmortem Examination of Patients With COVID-19

Olfactory Dysfunction in COVID-19

Seroprevalence of SARS-CoV-2–Specific Antibodies Among Adults in Los Angeles County, California, on April 10-11, 2020

Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults

Labor and Delivery Visitor Policies During the COVID-19 Pandemic

Translating Science on COVID-19 to Improve Clinical Care and Support the Public Health Response

Prioritizing Physician Mental Health as COVID-19 Marches On

Digital Smartphone Tracking for COVID-19

Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection

Comparison of Clinical Characteristics of Patients with Asymptomatic vs Symptomatic Coronavirus Disease 2019 in Wuhan, China

Coronavirus Disease 2019 Test Results After Clinical Recovery and Hospital Discharge Among Patients in China

Modeling Epidemics With Compartmental Models

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure

Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19

Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain

Anthony Fauci, MD, on COVID-19 Vaccines, Schools, and Larry Kramer

Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City

Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019

Renin-Angiotensin-Aldosterone Inhibitors and Susceptibility to and Severity of COVID-19

Temperature, Humidity, and Latitude Analysis to Estimate Potential Spread and Seasonality of Coronavirus Disease 2019 (COVID-19)

Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality

Thromboelastographic Results and Hypercoagulability Syndrome in Patients With Coronavirus Disease 2019 Who Are Critically Ill

Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020

Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza

Neurologic and Radiographic Findings Associated With COVID-19 Infection in Children

Is a “Cytokine Storm” Relevant to COVID-19?

Mortality and Morbidity

Cognitive Bias and Public Health Policy During the COVID-19 Pandemic

Excess Deaths From COVID-19 and Other Causes, March-April 2020

Benefits and Safety of Nasal Saline Irrigations in a Pandemic—Washing COVID-19 Away

Fear of Coronavirus Disease 2019—An Emerging Cardiac Risk

Presence of Genetic Variants Among Young Men With Severe COVID-19

Ketoacidosis in Children and Adolescents With Newly Diagnosed Type 1 Diabetes During the COVID-19 Pandemic in Germany

Molecular Underpinnings of Severe Coronavirus Disease 2019

Pooling Data From Individual Clinical Trials in the COVID-19 Era

Serosurveillance and the COVID-19 Epidemic in the US

Trends in US Heart Transplant Waitlist Activity and Volume During the Coronavirus Disease 2019 (COVID-19) Pandemic

Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System

Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers

COVID-19 and Dexamethasone A Potential Strategy to Avoid Steroid-Related Strongyloides Hyperinfection

Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19)

Prevalence of SARS-CoV-2 Antibodies in Health Care Personnel in the New York City Area

Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency

SARS-CoV-2 Testing and Changes in Primary Care Services in a Multistate Network of Community Health Centers During the COVID-19 Pandemic

Emergency Use Authorizations During the COVID-19 Pandemic Lessons From Hydroxychloroquine for Vaccine Authorization and Approval

Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

Clinical Outcomes in Young US Adults Hospitalized With COVID-19

Flipping the Script for Coronavirus Disease 2019 Contact Tracing

National Academies Offers Strategies to Encourage Cooperation in COVID-19 Contact Tracing

COVID-19 and the Path to Immunity

Cardiovascular Magnetic Resonance Findings in Competitive Athletes Recovering From COVID-19 Infection

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19

In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2

SARS-CoV-2 Nasopharyngeal Swab Testing—False-Negative Results From a Pervasive Anatomical Misconception

Frequency of Children vs Adults Carrying Severe Acute Respiratory Syndrome Coronavirus 2 Asymptomatically

Should We Mandate a COVID-19 Vaccine for Children?

Oncology Clinical Transformation in Response to the COVID-19 Pandemic

Опубликовано: Johns Hopkins Bloomberg School of Public Health

Five Variables that Can Affect COVID-19 Symptoms, Prognosis, and Outcomes

Опубликовано: Mayo Clinic Proceedings

Urgent Guidance for Navigating and Circumventing the QTc Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for COVID-19

Опубликовано: Medical Xpress

COVID-19 death counts 'substantial underestimation' of actual deaths for some Italian regions

Placentas from COVID-19-positive pregnant women show injury

Study suggests wastewater at treatment plants can be used as a barometer for COVID-19 infection rates

Faster identification and isolation of COVID-19 symptomatic individuals found to shorten average serial interval

Scientists discover key element of strong antibody response to COVID-19

We thought COVID-19 was just a respiratory virus—we were wrong

Опубликовано: medRxiv

Presence of SARS-CoV-2 reactive T cells in COVID-19 patients and healthy donors

Опубликовано: Nature

COVID-19 and the cardiovascular system

Pick of the coronavirus papers: Immune system shows abnormal response to COVID-19

The race for coronavirus vaccines: a graphical guide

Convalescent serum lines up as first-choice treatment for coronavirus

A human monoclonal antibody blocking SARS-CoV-2 infection

Profile of a killer: the complex biology powering the coronavirus pandemic

An interpretable mortality prediction model for COVID-19 patients

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

Опубликовано: National Institutes of Health (NIH)

NIH clinical trial shows Remdesivir accelerates recovery from advanced COVID-19

NIH begins clinical trial of hydroxychloroquine and azithromycin to treat COVID-19

Peer-reviewed data shows remdesivir for COVID-19 improves time to recovery

Experimental COVID-19 vaccine safe, generates immune response

Experimental COVID-19 vaccine protects upper and lower airways in nonhuman primates

NIH clinical trial testing remdesivir plus interferon beta-1a for COVID-19 treatment begins

Phase 3 Clinical Testing in the US of AstraZeneca COVID-19 Vaccine Candidate Begins

Опубликовано: NIH Director's Blog

Enlisting Monoclonal Antibodies in the Fight Against COVID-19

Will Warm Weather Slow Spread of Novel Coronavirus?

First Molecular Profiles of Severe COVID-19 Infections

Researchers Publish Encouraging Early Data on COVID-19 Vaccine

Immune T Cells May Offer Lasting Protection Against COVID-19

Study Ties COVID-19-Related Syndrome in Kids to Altered Immune System

Опубликовано: New England Journal of Medicine

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

Опубликовано: PubMed

Protecting Healthcare Workers From SARS-CoV-2 Infection: Practical Indications

Опубликовано: Science

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

Reducing transmission of SARS-CoV-2

Combination prevention for COVID-19

Serology assays to manage COVID-19

Rapid repurposing of drugs for COVID-19

Ethics and governance for digital disease surveillance

Susceptible supply limits the role of climate in the early SARS-CoV-2 pandemic

Which interventions work best in a pandemic?

Introductions and early spread of SARS-CoV-2 in the New York City area

A strategic approach to COVID-19 vaccine R&D

Inhibition of Bruton tyrosine kinase in patients with severe COVID-19

The story of COVID-19: A comparative analysis

An ACE therapy for COVID-19

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

Опубликовано: The Lancet

COVID-19: consider cytokine storm syndromes and immunosuppression

Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study

Опубликовано: The Liverpool Drug Interaction Group

Interactions with Experimental COVID-19 Therapies (PART1)

Interactions with Experimental COVID-19 Therapies (PART2)

Опубликовано: Wiley Online Library

Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

Последнее изменение: 22 сентября 2020 07:05

Информация для клиницистов